Specific IgA Enhances the Transcytosis and Excretion of Hepatitis A Virus

Abstract

Hepatitis A virus (HAV) replicates in the liver, and is excreted from the body in feces. However, the mechanisms of HAV transport from hepatocytes to the gastrointestinal tract are poorly understood, mainly due to lack of suitable in vitro models. Here, we use a polarized hepatic cell line and in vivo models to demonstrate vectorial transport of HAV from… (More)
DOI: 10.1038/srep21855

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Cite this paper

@inproceedings{Counihan2016SpecificIE, title={Specific IgA Enhances the Transcytosis and Excretion of Hepatitis A Virus}, author={Natalie A Counihan and David A. Anderson}, booktitle={Scientific reports}, year={2016} }