Specific GABAA circuits for visual cortical plasticity.


Weak inhibition within visual cortex early in life prevents experience-dependent plasticity. Loss of responsiveness to an eye deprived of vision can be initiated prematurely by enhancing gamma-aminobutyric acid (GABA)-mediated transmission with benzodiazepines. Here, we use a mouse "knockin" mutation to alpha subunits that renders individual GABA type A… (More)


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@article{Fagiolini2004SpecificGC, title={Specific GABAA circuits for visual cortical plasticity.}, author={Michela Fagiolini and Jean-Marc Fritschy and Karin L{\"o}w and Hanns M{\"o}hler and Uwe Rudolph and Takao K Hensch}, journal={Science}, year={2004}, volume={303 5664}, pages={1681-3} }