Specific DNA probe for the diagnosis of Plasmodium falciparum malaria.

@article{Barker1986SpecificDP,
  title={Specific DNA probe for the diagnosis of Plasmodium falciparum malaria.},
  author={Robert H. Barker and Laksami Suebsaeng and W. Rooney and G C Alecrim and H V Dourado and Dyann F Wirth},
  journal={Science},
  year={1986},
  volume={231 4744},
  pages={1434-6}
}
Malaria can be diagnosed either by direct microscopic examination of blood smears, which is time consuming and requires expertise, or by immunological techniques, which are effective but do not distinguish between past and present infections. In this study, a simple procedure was developed for spotting lysed blood from infected patients directly onto nitrocellulose paper and identifying the malaria species on the basis of hybridization of parasite DNA with a species-specific probe. A genomic… CONTINUE READING