Specific, Sensitive, and Quantitative Enzyme-Linked Immunosorbent Assay for Human Immunoglobulin G Antibodies to Anthrax Toxin Protective Antigen

@inproceedings{Quinn2002SpecificSA,
  title={Specific, Sensitive, and Quantitative Enzyme-Linked Immunosorbent Assay for Human Immunoglobulin G Antibodies to Anthrax Toxin Protective Antigen},
  author={Conrad P Quinn and Vera A. Semenova and Cheryl M. Elie and Sandra Romero-Steiner and Carolyn M. Greene and H Li and Karen L Stamey and Evelene Steward-Clark and Daniel S. Schmidt and Elizabeth A Mothershed and Janet M. Pruckler and Stephanie B Schwartz and Robert F. Benson and Leta O. Helsel and Patricia F Holder and Scott E. Johnson and Molly E. Kellum and Trudy O. Messmer and W. Lanier Thacker and Lilah M. Besser and Brian D. Plikaytis and Thomas H. Taylor and Alison E. Freeman and Kelly J. Wallace and Peter M. Dull and Jim Sejvar and Erica Bruce and Rosa Moreno and Anne Schuchat and Jairam R Lingappa and S. K. Saint Martin and John E. Walls and Melinda A. Bronsdon and George M. Carlone and Mary Bajani-Ari and David A. Ashford and David S. Stephens and Bradley A. Perkins},
  booktitle={Emerging infectious diseases},
  year={2002}
}
The bioterrorism-associated human anthrax epidemic in the fall of 2001 highlighted the need for a sensitive, reproducible, and specific laboratory test for the confirmatory diagnosis of human anthrax. The Centers for Disease Control and Prevention developed, optimized, and rapidly qualified an enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G (IgG) antibodies to Bacillus anthracis protective antigen (PA) in human serum. The qualified ELISA had a minimum detection limit of 0.06… CONTINUE READING

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The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax.

  • FEMS immunology and medical microbiology
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No evidence of a mild form of inhalational Bacillus anthracis infection during a bioterrorism-related inhalational anthrax outbreak in Washington, D.C., in 2001.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2005
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