Species variation in the ouabain sensitivity of cardiac Na+/K+-ATPase. A possible role for membrane lipids.

@article{Abeywardena1984SpeciesVI,
  title={Species variation in the ouabain sensitivity of cardiac Na+/K+-ATPase. A possible role for membrane lipids.},
  author={Mahinda Yapa Abeywardena and E. J. Mcmurchie and G. R. Russell and John S. Charnock},
  journal={Biochemical pharmacology},
  year={1984},
  volume={33 22},
  pages={3649-54}
}
The role of membrane lipid composition on the modulation of ouabain sensitivity of cardiac Na+/K+-ATPase has been studied in vitro using several animal species. The animals can be grouped as ouabain-sensitive and ouabain-insensitive species. Ouabain-sensitive species (I50; 0.5-2.2 microM) include sheep, marmoset, pig and the guinea pig, whilst rat and mouse form the ouabain-insensitive group (I50; 100-105 microM). Although no species variation in the distribution of major phospholipid classes… CONTINUE READING

From This Paper

Topics from this paper.
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…