Species-specific uptake of DNA by gonococci is mediated by a 10-base-pair sequence.

  title={Species-specific uptake of DNA by gonococci is mediated by a 10-base-pair sequence.},
  author={Christopher Elkins and Christopher Thomas and H Steven Seifert and P. Frederick Sparling},
  journal={Journal of bacteriology},
  volume={173 12},
Piliated Neisseria gonorrhoeae are known to be transformed less readily if transforming DNA competes with DNA containing the 10-bp sequence GCCGTCTGAA. It has been postulated that the 10-bp sequence is a recognition sequence which is required for efficient DNA uptake. We show that the presence of various forms of this 10-bp sequence results in increased uptake of double-stranded DNA into a DNase-resistant state and allows genetic transformation by an otherwise nontransformable plasmid. 

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Gene structure and extracellular secretion in Neisseria gonorrhoeae

  • H. S. Seifert, E. Y. Chen, M. So, F. Heffron
  • Nature ( London )
  • 1987

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