Species-specific evolution of the FcR family in endothermic vertebrates

  title={Species-specific evolution of the FcR family in endothermic vertebrates},
  author={Svetlana A. Fayngerts and Alexander M. Najakshin and Alexander V. Taranin},
In primates and rodents, the extended FcR family is comprised of three subsets: classical FcRs, structurally diverse cell surface receptors currently designated FCRL1–FCRL6, and intracellular proteins FCRLA and FCRLB. Using bioinformatic analysis, we revealed the FcR-like genes of the same three subsets in the genome of dog, another representative of placental mammals, and in the genome of short-tailed opossum, a representative of marsupials. In contrast, a single FcR-like gene was found in the… CONTINUE READING
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