Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer.

@article{Bank1992SpeciesspecificBO,
  title={Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer.},
  author={P A Bank and Eiya Yao and Cynthia L. Phelps and Patricia A. Harper and Michael S. Denison},
  journal={European journal of pharmacology},
  year={1992},
  volume={228 2-3},
  pages={85-94}
}
The Ah receptor (AhR) mediates many, if not all, of the toxic and biological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and related halogenated aromatic hydrocarbons. Although wide variations in species sensitivity to these compounds have been observed, numerous biochemical and physiochemical characteristics of the AhR appear similar among species. We have examined the ability of cytosolic AhR, from a variety of species (rat, rabbit, guinea pig, hamster, mouse, cow, sheep… CONTINUE READING

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