Species differences in affinities of non-peptide antagonists for substance P receptors.

@article{Gitter1991SpeciesDI,
  title={Species differences in affinities of non-peptide antagonists for substance P receptors.},
  author={Bruce D. Gitter and Dic Waters and Robert F. Bruns and Norman R. Mason and John Alexander Nixon and James Jeffry Howbert},
  journal={European journal of pharmacology},
  year={1991},
  volume={197 2-3},
  pages={
          237-8
        }
}
In the present study, affinities of (±)-CP-96,345 and analogs in [ 125 I]SP binding were determined in various tissues derived from several species. The resulting IC 50 values segregate into discrete groups according to species rather than tissue, indicating the existence of species differences in NK-1 receptors 
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