Species differences in NO formation by rat and hamster alveolar macrophages in vitro.

@article{Doerger1997SpeciesDI,
  title={Species differences in NO formation by rat and hamster alveolar macrophages in vitro.},
  author={Martina Doerger and Netalie K Jesch and Gabriele Rieder and M R Hirvonen and K. Savolainen and Fritz Krombach and K. Me\ssmer},
  journal={American journal of respiratory cell and molecular biology},
  year={1997},
  volume={16 4},
  pages={413-20}
}
Nitric oxide (NO) is a cellular mediator and regulator of multiple biologic functions. NO released by alveolar macrophages (AM) is suggested to play a role in mediating pulmonary injury. In murine and rat macrophages, the expression of inducible NO synthase (iNOS) and the release of NO are well established. However, the existence of such a pathway in other species remains controversial. In this study, we examined NO production and iNOS expression by AM from rats and hamsters, two laboratory… CONTINUE READING