Species difference of esterase expression and hydrolase activity in plasma.

@article{Bahar2012SpeciesDO,
  title={Species difference of esterase expression and hydrolase activity in plasma.},
  author={Fatma Goksin Bahar and Kayoko Ohura and Takuo Ogihara and Teruko Imai},
  journal={Journal of pharmaceutical sciences},
  year={2012},
  volume={101 10},
  pages={
          3979-88
        }
}
Differences in esterase expression among human, rhesus monkey, cynomolgus monkey, dog, minipig, rabbit, rat, and mouse plasma were identified using native polyacrylamide gel electrophoresis. Paraoxonase (PON) and butyrylcholinesterase (BChE) were ubiquitous in all species, but were highly expressed in primates and dogs, whereas carboxylesterase (CES) was only abundant in rabbits, mice, and rats. Several unknown esterases were observed in minipig and mouse plasma. These differences in plasma… CONTINUE READING
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