Species difference in sensitivity to the diabetogenic action of triphenyltin hydroxide

@article{Matsui1984SpeciesDI,
  title={Species difference in sensitivity to the diabetogenic action of triphenyltin hydroxide},
  author={Hideki Asoh zToshihiro Matsui and Osamu Wada and Sunao Manabe and Yasuhiko Ushijima and Tomoyuki Fujikura},
  journal={Experientia},
  year={1984},
  volume={40},
  pages={377-378}
}
The sensitivity to the diabetogenic action of triphenyltin hydroxide (TPTOH) was investigated in 5 species of experimental animals. A single oral administration of TPTOH produced marked hyperglycemia and triglyccridemia in rabbits and hamsters, but no evidence of diabetes was found in mice, rats and guinea-pigs. No morphological abnormality was observed in islet tissue from TPTOH-treated hamsters. 

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