Species-Specific and Cross-Reactive IgG1 Antibody Binding to Viral Capsid Protein 1 (VP1) Antigens of Human Rhinovirus Species A, B and C

@inproceedings{Iwasaki2013SpeciesSpecificAC,
  title={Species-Specific and Cross-Reactive IgG1 Antibody Binding to Viral Capsid Protein 1 (VP1) Antigens of Human Rhinovirus Species A, B and C},
  author={Jua Iwasaki and W C Smith and Shane R. Stone and Wayne Robert Thomas and Belinda J Hales},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children and adults. Although the clinical significance of HRV infections is now well established, no detailed investigation of the immune response against HRV has been performed. The purpose of this study was to assess the IgG1 antibody response to the three known HRV species, HRV-A, -B and -C in healthy subjects. METHODS Recombinant… CONTINUE READING