Special Report: Reproductive and Developmental Toxicity of Ethylene Glycol and Its Ethers

  title={Special Report: Reproductive and Developmental Toxicity of Ethylene Glycol and Its Ethers},
  author={F. Alan Andersen},
  journal={International Journal of Toxicology},
  pages={53 - 67}
  • F. A. Andersen
  • Published 1 March 1999
  • Chemistry
  • International Journal of Toxicology
Polymers of Ethylene Glycol are linked via ether linkages with various alcohols or via ester linkages to various fatty acids in many cosmetic ingredients. Ethylene Glycol, when reacted with an alkyl alcohol, forms an ethylene glycol monoalkyl ether. These compounds are metabolized in the human body by alcohol dehydrogenase and aldehyde dehydrogenase to form corresponding acetaldehyde and acetic acid derivatives. Data are presented that show reproductive and developmental toxicity is associated… 

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