Speaking without Broca's area after tumor resection

@article{Plaza2009SpeakingWB,
  title={Speaking without Broca's area after tumor resection},
  author={Monique Plaza and Peggy Gatignol and Marianne Leroy and Hugues Duffau},
  journal={Neurocase},
  year={2009},
  volume={15},
  pages={294 - 310}
}
We present the case of a right-handed patient who received surgical treatment for a left frontal WHO grade II glioma invading the left inferior and middle frontal gyri, the head of the caudate nucleus, the anterior limb of the internal capsule and the anterior insula, in direct contact also with the anterior-superior part of the lentiform nucleus. The tumor resection was guided by direct electrical stimulation on brain areas, while the patient was awake. Adding a narrative production task to… 

A case of bilateral frontal tumors without “frontal syndrome”

The longitudinal case study of a right-handed patient harboring two frontal tumors that benefited from bilateral simultaneous surgery reveals the significance of brain plasticity in the reorganization of cognitive networks, even in cases of bilateral tumors and confirms the clinical relevance of hodotopical brain models.

Dissociated Crossed Speech Areas in a Tumour Patient

A 41-year-old, left-handed man with a low-grade glioma in the left frontal operculum extending to the insular cortex, tension headaches, and anomic aphasia over 5 months underwent a pre-operative speech area localisation fMRI measurement, which revealed the evidence of the transhemispheric disposition.

Resection of glioma in an fMRI-defined “split” Broca’s area

Intraoperative mapping and intraoperative magnetic resonance imaging allowed gross total resection of the tumor with preservation of language function and illustrate the utility of multiple contemporary modalities in the surgical management of low-grade gliomas located in eloquent cortices.

Limited plastic potential of the left ventral premotor cortex in speech articulation: Evidence From intraoperative awake mapping in glioma patients

The original data suggest that the vPMC plays a crucial role in the speech production network and that its plastic potential is limited, and it is proposed that this limitation is due to an anatomical constraint, namely the necessity for the left v PMC to remain connected to the lateral SLF.

Advances in the surgical resection of temporo-parieto-occipital junction gliomas

Tumor location-based classification of surgery-related language impairments in patients with glioma

According to this study's classification, patients with type II tumors had the worst language prognosis and longest recovery time and may be used to guide tumor resection.

The Impact of Left Temporal Lobe Glioma on Inner Speech

Background: Inner speech has an important role in many human cognitive functions. Even though it has been extensively studied in post-stroke aphasic patients, there is currently no understanding on

Frontal operculum gliomas: language outcome following resection.

Given the low rate of language morbidity reported in this group of patients, resection of gliomas within the dominant frontal operculum is well-tolerated with acceptable morbidity and, in this particular location, should not be a deterrent in the overall management of these tumors.
...

References

SHOWING 1-10 OF 80 REFERENCES

Training-induced brain plasticity in aphasia.

This study supports the role of the right hemisphere in recovery from aphasia and demonstrates that the improvement in auditory comprehension induced by specific training is associated with functional brain reorganization.

Role of the Right and Left Hemispheres in Recovery of Function during Treatment of Intention in Aphasia

Two patients with residual nonfluent aphasia after ischemic stroke received an intention treatment that was designed to shift intention and language production mechanisms from the frontal lobe of the damaged left hemisphere to the right frontal lobe, and the first patient showed improvement on the intention treatment but not on a similar attention treatment.

Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients.

There is a need for revision of the classical model of language localization, for it means that language cannot be reliably localized on anatomic criteria alone and a maximal resection with minimal risk of postoperative aphasia requires individual localization of language with a technique like stimulation mapping.

Distinct right frontal lobe activation in language processing following left hemisphere injury.

Right hemisphere activation during functional imaging studies of language has frequently been reported following left hemisphere injury. Few studies have anatomically characterized the specific right

The Ruff 2 and 7 Selective Attention Test: A Neuropsychological Application

The neuropsychological application of the Ruff 2 and 7 Selective Attention Test as a measure of visual selective attention was investigated and it was predicted that the two groups with anterior brain damage showed a larger discrepancy between serial and parallel processing modes than patients with posterior lesions.

Recovery from nonfluent aphasia after melodic intonation therapy

The idea that abnormal activation patterns in the lesioned brain are not necessarily related to the recovery process is supported, as the right hemisphere regions abnormally activated during simple language tasks seem to be associated with the initial persistence of the aphasia.

A discrete area within the left dorsolateral prefrontal cortex involved in visual-verbal incongruence judgment.

The dissociation observed between correct picture naming and disturbed cross-modal judgment shows that electrical stimulation of a discrete cortical area within the left dorsolateral prefrontal cortex can inhibit the simultaneous processing of visual-verbal information without disturbing larger networks involved in the naming process.

Contrasting acute and slow-growing lesions: a new door to brain plasticity.

This paper addresses the idea that brain plasticity cannot be fully understood and fruitfully studied without considering the temporal pattern of the injury inflicted to the brain and shows that functional recovery is considerably better in the context of slow-growing injuries than after acute lesions.

Semantic Processing in the Left Inferior Prefrontal Cortex: A Combined Functional Magnetic Resonance Imaging and Transcranial Magnetic Stimulation Study

The results clarify the functional anatomy of the LIPC by demonstrating that anterior and posterior regions contribute to both semantic and phonological processing, albeit to different extents.
...