Spatiotemporally controlled genetic perturbation for 1 efficient large-scale studies of cell non-autonomous effects 2 3 4

@inproceedings{ChaiSpatiotemporallyCG,
  title={Spatiotemporally controlled genetic perturbation for 1 efficient large-scale studies of cell non-autonomous effects 2 3 4},
  author={Andrea Ying Ying Chai and Ana Margarida Mateus and Fazal Oozeer and Rita Sousa-Nunes}
}
23 Studies in genetic model organisms have revealed much about the 24 development and pathology of complex tissues. Most have focused on cell25 intrinsic gene functions and mechanisms. Much less is known about how 26 transformed, or otherwise functionally disrupted, cells interact with 27 healthy ones towards a favorable or pathological outcome. This is largely 28 due to technical limitations. We developed new genetic tools in Drosophila 29 melanogaster that permit efficient multiplexed gainand… CONTINUE READING

Similar Papers

References

Publications referenced by this paper.