Spatiotemporal profile of N-cadherin expression in the mossy fiber sprouting and synaptic plasticity following seizures

@article{Lin2011SpatiotemporalPO,
  title={Spatiotemporal profile of N-cadherin expression in the mossy fiber sprouting and synaptic plasticity following seizures},
  author={Hua Lin and Yuangui Huang and Yu-Ping Wang and Jianping Jia},
  journal={Molecular and Cellular Biochemistry},
  year={2011},
  volume={358},
  pages={201-205}
}
Recurrent seizures can induce mossy fiber sprouting (MFS), of the hippocampal dentate gyrus, and synaptic reorganization in mature brain. This changes local circuits and provides a structural basis for epileptogenesis in the hippocampus. However, the mechanisms of MFS and synaptic reorganization still remain unclear. Neural-cadherin (N-cadherin), a calcium… CONTINUE READING