Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal).

  title={Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal).},
  author={T{\^a}nia Vieira Madureira and Juliana Cristina Barreiro and Maria Jo{\~a}o Rocha and Eduardo Rocha and Quezia B Cass and Maria Elizabeth Tiritan},
  journal={The Science of the total environment},
  volume={408 22},
The amount and distribution of six pharmaceutical compounds belonging to distinct therapeutic classes were investigated along the navigation channel of the Douro River estuary. Distinct spatial and temporal trends were considered and a total of 87 water samples were pre-concentrated by solid-phase extraction (SPE) and analyzed by liquid chromatography tandem mass spectrometry (LC-MS/MS) with an ion trap (IT) analyzer and electrospray ionization (ESI). The maximum concentrations found were 178ng… CONTINUE READING
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