Spatiotemporal delivery strategies for promoting musculoskeletal tissue regeneration.

@article{Guldberg2009SpatiotemporalDS,
  title={Spatiotemporal delivery strategies for promoting musculoskeletal tissue regeneration.},
  author={Robert Erling Guldberg},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2009},
  volume={24 9},
  pages={1507-11}
}
A primary regenerative medicine strategy is to stimulate or augment endogenous repair mechanisms that promote functional restoration of damaged or degenerated tissues. There is increasing evidence that maximizing the potency of tissue regenerative therapies will require design and development of delivery approaches that provide controlled spatiotemporal release of key signaling molecules. Guidance on which factors to deliver and the timing of delivery is emerging from advances in understanding… CONTINUE READING

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