Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

  title={Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate},
  author={York Posor and Marielle Eichhorn-Gruenig and Dmytro Puchkov and Johannes Sch{\"o}neberg and Alexander Ullrich and Andr{\'e} Lampe and Rainer M{\"u}ller and Sirus Zarbakhsh and Federico Gulluni and Emilio Hirsch and Michael Krauss and Carsten Schultz and Jan Schmoranzer and Frank No{\'e} and Volker Haucke},
Phosphoinositides serve crucial roles in cell physiology, ranging from cell signalling to membrane traffic. Among the seven eukaryotic phosphoinositides the best studied species is phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2), which is concentrated at the plasma membrane where, among other functions, it is required for the nucleation of endocytic… CONTINUE READING