Spatiotemporal alteration of phospholipids and prostaglandins in a rat model of spinal cord injury.

@article{Hanada2012SpatiotemporalAO,
  title={Spatiotemporal alteration of phospholipids and prostaglandins in a rat model of spinal cord injury.},
  author={Mitsuru Hanada and Yuki Sugiura and Ryuichi Shinjo and Noritaka Masaki and Shiro Imagama and Naoki Ishiguro and Yukihiro Matsuyama and Mitsutoshi Setou},
  journal={Analytical and bioanalytical chemistry},
  year={2012},
  volume={403 7},
  pages={1873-84}
}
We determined quantitative and qualitative alterations in lipids during the occurrence and progression of spinal cord injury (SCI) in rats to identify potential clinical indicators of SCI pathology. Imaging mass spectrometry (IMS) was used to visualize twelve molecular species of phosphatidylcholine (PC) on thin slices of spinal cord with SCI. In addition, twelve species of phospholipids and five species of prostaglandins (PGs) were quantified by liquid chromatography-electrospray ionization… CONTINUE READING

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