Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations

@article{Yang2017SpatiotemporalEO,
  title={Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations},
  author={Z. Yang and Yuanyuan Geng and Zhiya Yao and Huimin Jia and Y. Bai and Weilin Wang},
  journal={Neurochemical Research},
  year={2017},
  volume={42},
  pages={3160-3169}
}
  • Z. Yang, Yuanyuan Geng, +3 authors Weilin Wang
  • Published 2017
  • Biology, Medicine
  • Neurochemical Research
    • Fecal incontinence and constipation still remain the major complications after procedures for anorectal malformations (ARMs). Previous studies have demonstrated a decrease of neural cell in lumbosacral spinal cord of ARMs patients and rat models. However, the underlying mechanism remains elusive. In this study, the neural cell apoptosis and Bcl-2/Bax expression were explored during lumbosacral spinal cord development in normal and ARMs fetuses. ARMs rat fetuses were induced by treating pregnant… CONTINUE READING
    View on Springer
    ncbi.nlm.nih.gov
    9 Citations
    Background Citations
    2
    9 Citations
    Citation Type

    Citation Type

    Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats
    Involvement of proliferative and apoptotic factors in the development of hindgut in rat fetuses with ethylenethiourea-induced anorectal malformations.
    Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations
    • 2
    The Expression of Shh, Ptch1, and Gli1 in the Developing Caudal Spinal Cord of Fetal Rats With Anorectal Malformations.
    • 3
    MSX2 and BCL2 expressions in the development of anorectal malformations in ethylenethiourea-induced rat embryos.
    • 2
    BMP7 Is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
    Maternal folic acid deficiency stimulates neural cell apoptosis via miR-34a associated with Bcl-2 in the rat foetal brain
    • 6
    Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox.
    • Luqing Cui, D. Xing, +11 authors Z. Yuan
    • Chemistry, Medicine
    • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
    • 2018
    • 3
    Effects of a Subchronic Intoxication with Cadmium in the Hippocampus of Rats Fed a Soybean-Based Diet
    • PDF

    References

    SHOWING 1-10 OF 34 REFERENCES
    Apoptosis during the development of pelvic floor muscle in anorectal malformation rats.
    • 12
    Wnt5a expression in the hindgut of fetal rats with chemically induced anorectal malformations—studies in the ETU rat model
    • 12
    Embryonic development of the striated muscle complex in rats with anorectal malformations.
    • 21
    Expression of EphB2 in the development of anorectal malformations in fetal rats.
    • 7
    Abnormal innervation patterns in the anorectum of ETU-induced fetal rats with anorectal malformations
    • 4
    Embryonic development of the internal anal sphincter in rats with anorectal malformations.
    • 11
    Spatiotemporal pattern analysis of transcription factor 4 in the developing anorectum of the rat embryo with anorectal malformations
    • 11
    Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system
    • 130
    • PDF
    Clarification of the processes that lead to anorectal malformations in the ETU-induced rat model of imperforate anus.
    • 50
    Hoxd-13 expression in the development of hindgut in ethylenethiourea-exposed fetal rats.
    • 12