Spatiotemporal Alterations in Primary Odorant Representations in Olfactory Marker Protein Knockout Mice

@inproceedings{Kass2013SpatiotemporalAI,
  title={Spatiotemporal Alterations in Primary Odorant Representations in Olfactory Marker Protein Knockout Mice},
  author={Marley D. Kass and Andrew H. Moberly and John P McGann},
  booktitle={PloS one},
  year={2013}
}
Olfactory marker protein (OMP) is highly and selectively expressed in primary olfactory sensory neurons (OSNs) across species, but its physiological function remains unclear. Previous studies in the olfactory epithelium suggest that it accelerates the neural response to odorants and may modulate the odorant-selectivity of OSNs. Here we used a line of gene-targeted mice that express the fluorescent exocytosis indicator synaptopHluorin in place of OMP to compare spatiotemporal patterns of odorant… CONTINUE READING

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