Spatio-temporal image correlation spectroscopy and super-resolution microscopy to quantify molecular dynamics in T cells.

@article{Ashdown2018SpatiotemporalIC,
  title={Spatio-temporal image correlation spectroscopy and super-resolution microscopy to quantify molecular dynamics in T cells.},
  author={George W. Ashdown and Dylan M. Owen},
  journal={Methods},
  year={2018},
  volume={140-141},
  pages={
          112-118
        }
}
Many cellular processes are regulated by the spatio-temporal organisation of signalling complexes, cytoskeletal components and membranes. One such example is at the T cell immunological synapse where the retrograde flow of cortical filamentous (F)-actin from the synapse periphery drives signalling protein microclusters towards the synapse centre. The… CONTINUE READING