Spatio-Temporal Tracking and Phylodynamics of an Urban Dengue 3 Outbreak in São Paulo, Brazil

@article{Mondini2009SpatioTemporalTA,
  title={Spatio-Temporal Tracking and Phylodynamics of an Urban Dengue 3 Outbreak in S{\~a}o Paulo, Brazil},
  author={Adriano Mondini and Roberta Vieira de Moraes Bronzoni and Silvia Helena Pereira Nunes and Francisco Chiaravalloti Neto and Eduardo Massad and Wladimir J Alonso and Eduardo S. M. L{\'a}zzaro and Amena Alc{\^a}ntara Ferraz and Paolo Marinho de Andrade Zanotto and Maur{\'i}cio Lacerda Nogueira},
  journal={PLoS Neglected Tropical Diseases},
  year={2009},
  volume={3},
  pages={961 - 1034}
}
The dengue virus has a single-stranded positive-sense RNA genome of approximately 10.700 nucleotides with a single open reading frame that encodes three structural (C, prM, and E) and seven nonstructural (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) proteins. It possesses four antigenically distinct serotypes (DENV 1-4). Many phylogenetic studies address particularities of the different serotypes using convenience samples that are not conducive to a spatio-temporal analysis in a single urban… CONTINUE READING
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