Spatially varying regularization based on spectrally resolved fluorescence emission in fluorescence molecular tomography.

@article{Axelsson2007SpatiallyVR,
  title={Spatially varying regularization based on spectrally resolved fluorescence emission in fluorescence molecular tomography.},
  author={Johan Axelsson and Jenny Svensson and Stefan Andersson-Engels},
  journal={Optics express},
  year={2007},
  volume={15 21},
  pages={13574-84}
}
Fluorescence molecular tomography suffers from being mathematically ill-conditioned resulting in non-unique solutions to the reconstruction problem. In an attempt to reduce the number of possible solutions in the underdetermined system of equations in the reconstruction, we present a method to retrieve a spatially varying regularization map outlining the feasible inclusion position. This approach can be made very simple by including a few multispectral recordings from only one source position… CONTINUE READING

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