Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY.

Abstract

Understanding how boundaries and domains of Hox gene expression are determined is critical to elucidating the means by which the embryo is patterned along the anteroposterior axis. We have performed a detailed analysis of the mouse Hoxb4 intron enhancer to identify upstream transcriptional regulators. In the context of an heterologous promoter, this… (More)

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