Spatially regulated SpEts4 transcription factor activity along the sea urchin embryo animal-vegetal axis.

Abstract

Because the transcription of the SpHE gene is regulated cell-autonomously and asymmetrically along the maternally determined animal-vegetal axis of the very early sea urchin embryo, its regulators provide an excellent entry point for investigating the mechanism(s) that establishes this initial polarity. Previous studies support a model in which spatial… (More)

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