Spatially extended hybrid methods: a review

@article{Smith2018SpatiallyEH,
  title={Spatially extended hybrid methods: a review},
  author={Cameron A. Smith and Christian A. Yates},
  journal={Journal of the Royal Society Interface},
  year={2018},
  volume={15}
}
Many biological and physical systems exhibit behaviour at multiple spatial, temporal or population scales. Multiscale processes provide challenges when they are to be simulated using numerical techniques. While coarser methods such as partial differential equations are typically fast to simulate, they lack the individual-level detail that may be required in regions of low concentration or small spatial scale. However, to simulate at such an individual level throughout a domain and in regions… 
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