Spatially dynamic expression of Sry in mouse genital ridges.

@article{Bullejos2001SpatiallyDE,
  title={Spatially dynamic expression of Sry in mouse genital ridges.},
  author={Monica Bullejos and Peter Koopman},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2001},
  volume={221 2},
  pages={201-5}
}
We have studied the spatial dynamics of Sry transcription in the genital ridges of mouse embryos. We find that Sry is expressed in a dynamic wave that emanates from the central and/or anterior regions, extends subsequently to both poles, and ends in the caudal pole. This dynamism may explain the relative positioning of ovarian and testicular tissue seen in ovotestes in mice. Since direct regulatory targets of SRY ought to be expressed in a corresponding or complimentary wave, our observations… CONTINUE READING
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