Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus.

@article{Mojica2012SpatiallyAT,
  title={Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus.},
  author={Julius P. Mojica and Young Wha Lee and John H. Willis and John K. Kelly},
  journal={Molecular ecology},
  year={2012},
  volume={21 15},
  pages={3718-28}
}
Why do populations remain genetically variable despite strong continuous natural selection? Mutation reconstitutes variation eliminated by selection and genetic drift, but theoretical and experimental studies each suggest that mutation-selection balance insufficient to explain extant genetic variation in most complex traits. The alternative hypothesis of balancing selection, wherein selection maintains genetic variation, is an aggregate of multiple mechanisms (spatial and temporal heterogeneity… CONTINUE READING
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