Spatial strategy elaboration in egocentric and allocentric tasks following medial prefrontal cortex lesions in the rat.

Abstract

We evaluated the role of the medial prefrontal cortex (mPFC) in the elaboration of egocentric navigation strategies in a water maze (WM). Lesions of mPFC cell bodies was achieved in 21 rats using bilateral injections of ibotenic acid (IA); 13 control rats were injected with saline. After 17 days, rats had to learn an allocentric (using external cues: 10… (More)

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@article{Ethier2001SpatialSE, title={Spatial strategy elaboration in egocentric and allocentric tasks following medial prefrontal cortex lesions in the rat.}, author={Kathleen A. Ethier and Nathalie Le Marec and P P Rompr{\'e} and Rachel A Godbout}, journal={Brain and cognition}, year={2001}, volume={46 1-2}, pages={134-5} }