Spatial receptive fields in the retina and dorsal lateral geniculate nucleus of mice lacking rods and cones.

@article{Procyk2015SpatialRF,
  title={Spatial receptive fields in the retina and dorsal lateral geniculate nucleus of mice lacking rods and cones.},
  author={Christopher A. Procyk and Cyril G. Eleftheriou and Riccardo Storchi and Annette E Allen and Nina Milosavljevic and Timothy M Brown and Robert J Lucas},
  journal={Journal of neurophysiology},
  year={2015},
  volume={114 2},
  pages={1321-30}
}
In advanced retinal degeneration loss of rods and cones leaves melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) as the only source of visual information. ipRGCs drive non-image-forming responses (e.g., circadian photoentrainment) under such conditions but, despite projecting to the primary visual thalamus [dorsal lateral geniculate nucleus (dLGN)], do not support form vision. We wished to determine what precludes ipRGCs supporting spatial discrimination after… CONTINUE READING
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