Spatial profiling invertebrate ganglia using MALDI MS.

@article{Kruse2003SpatialPI,
  title={Spatial profiling invertebrate ganglia using MALDI MS.},
  author={Rebecca A. Kruse and Jonathan V. Sweedler},
  journal={Journal of the American Society for Mass Spectrometry},
  year={2003},
  volume={14 7},
  pages={752-9}
}
The ability of MALDI TOF MS to spatially map peptides and proteins directly from a tissue is an exciting advance to imaging mass spectrometry. Recent advances in instrumentation for MS have resulted in instruments capable of achieving several micron spatial resolution while acquiring high-resolution mass spectra. Currently, the ability to obtain high quality mass spectrometric images depends on sample preparation protocols that often result in limited spatial resolution. A number of sample… CONTINUE READING

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