Spatial pattern of MHC class II variation in the great snipe (Gallinago media).

@article{Ekblom2007SpatialPO,
  title={Spatial pattern of MHC class II variation in the great snipe (Gallinago media).},
  author={Robert Ekblom and Stein Are Saether and P{\"a}r Jacobsson and Peder Fiske and Tobias Sahlman and Mats Grahn and John Atle K{\aa}l{\aa}s and Jacob H{\"o}glund},
  journal={Molecular ecology},
  year={2007},
  volume={16 7},
  pages={1439-51}
}
The genes of the major histocompatibility complex (MHC) code for proteins involved in antigen recognition and triggering of the adaptive immune response, and are therefore likely to be under selection from parasites. These selection regimes may vary in space and time. Here we report a strong geographical structure in MHC class II B genes of a migrating bird, the great snipe (Gallinago media). Genetic differentiation in the MHC between two ecologically distinct distributional regions… CONTINUE READING