Spatial organization of repetitive DNA sequences in the bovine sperm nucleus.

  title={Spatial organization of repetitive DNA sequences in the bovine sperm nucleus.},
  author={D. J. Powell and Dr. D. G. Cran and C V Jennings and R Bradley Jones},
  journal={Journal of cell science},
  volume={97 ( Pt 1)},
During spermatogenesis, DNA in the sperm head becomes more tightly condensed as histones are replaced by protamine-like molecules. In this article, the question is asked whether, during the production of this highly differentiated cell, controls are imposed on the spatial organization of DNA within the nucleus. Heads from bull spermatozoa were isolated by a technique that removed the plasma membrane and acrosomal contents, and the DNA was induced to decondense by addition of 2-mercaptoethanol… CONTINUE READING


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