Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat

@article{Sutherland1982SpatialMD,
  title={Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat},
  author={Robert J Sutherland and Bryan E Kolb and Ian Q. Whishaw},
  journal={Neuroscience Letters},
  year={1982},
  volume={31},
  pages={271-276}
}
View on Elsevier
doi.org
539 Citations
Highly Influential Citations
5
Background Citations
96
Methods Citations
26
Results Citations
5

539 Citations

Citation Type

Citation Type

Dissociation of the contributions of the prefrontal cortex and dorsomedial thalamic nucleus to spatially guided behavior in the rat
Disruption of spatial but not object-recognition memory by neurotoxic lesions of the dorsal hippocampus in rats.
TLDR
The finding that partial hippocampal lesions disrupt spatial memory while leaving object-recognition memory intact indicates a specialized role for the hippocampus in mnemonic processes.
A behavioural analysis of rats with damage to the medial prefrontal cortex using the morris water maze: evidence for behavioural flexibility, but not for impaired spatial navigation
Hippocampal lesions and path integration
Double dissociation between hippocampal and prefrontal lesions on an operant delayed matching task and a water maze reference memory task
Early amygdala damage disrupts performance on medial prefrontal cortex-related tasks but spares spatial learning and memory in the rat
The Flexible Use of Multiple Cue Relationships in Spatial Navigation: A Comparison of Water Maze Performance Following Hippocampal, Medial Septal, Prefrontal Cortex, or Posterior Parietal Cortex Lesions
TLDR
The results suggest that the sham-operated control, posterior parietal cortex-lesioned rats, and medial septal area-LESioned rats were able to navigate effectively under changing task conditions and the navigational performances of the prefrontal cortex- and hippocampal formation-lesion rats were impaired when task demands changed.
Perirhinal cortex lesions produce retrograde but not anterograde amnesia for allocentric spatial information: Within-subjects examination
  • J. Ramos
  • Biology, Psychology
    Behavioural Brain Research
  • 2013
The role of medial prefrontal cortex in context-specific inhibition during reversal learning of a visual discrimination
TLDR
These and other results from a transfer test suggest that the medial prefrontal cortex participates in the behavioral effects of a context-specific inhibitory association acquired during visual discrimination learning.
A comparison of the contributions of the frontal and parietal association cortex to spatial localization in rats.
TLDR
The results suggest that the frontal andParietal cortex of rats play different roles in the control of spatial orientation but do not support the view that egocentric and allocentric spatial orientation are related to frontal and parietal mechanisms, respectively.
...
...

References

SHOWING 1-10 OF 27 REFERENCES
Fornix lesions selectively abolish place learning in the rat
Visually-guided maze learning in man: effects of bilateral hippocampal, bilateral frontal, and unilateral cerebral lesions
Tactually-guided maze learning in man: Effects of unilateral cortical excisions and bilateral hippocampal lesions ☆
Prefrontal system in the rat visualized by means of labeled deoxyglucose—further evidence for functional heterogeneity of the neostriatum
An epileptic focus was formed in the anteromedial part of the prefrontal cortex in rats by means of intracortical injection of penicillin, and radioactively labeled deoxyglucose was immediately…
Loss of Topographic Memory with Learning Deficits
The function of septo-hippocampal connections in spatially organized behaviour.
  • D. Olton
  • Biology, Psychology
    Ciba Foundation symposium
  • 1977
TLDR
Evidence suggests an important role of the septo-hippocampal system in spatial behaviour, and in the maintenance of spatial memories, is indicated and disruptive stimulation of the hippocampus while rats are performing a spatial memory task produces retrograde amnesia but not proactive interference.
A direct projection from Ammon's horn to prefrontal cortex in the rat
Non-spatial memory after selective prefrontal lesions in monkeys
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat.
A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat
...
...