Spatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography.

@article{Tran2014SpatialLO,
  title={Spatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography.},
  author={Erin E. Herbert Tran and James A. Simmons and Alberto Bartesaghi and Charles J. Shoemaker and Elizabeth A Nelson and Judith M White and S. Anand Subramaniam},
  journal={Journal of virology},
  year={2014},
  volume={88 18},
  pages={10958-62}
}
The Ebola virus glycoprotein mucin-like domain (MLD) is implicated in Ebola virus cell entry and immune evasion. Using cryo-electron tomography of Ebola virus-like particles, we determined a three-dimensional structure for the full-length glycoprotein in a near-native state and compared it to that of a glycoprotein lacking the MLD. Our results, which show that the MLD is located at the apex and the sides of each glycoprotein monomer, provide a structural template for analysis of MLD function. 
Highly Cited
This paper has 36 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…