Corpus ID: 25819982

Spatial localization of agonist-induced Ca2+ entry in bovine adrenal chromaffin cells. Different patterns induced by histamine and angiotensin II, and relationship to catecholamine release.

@article{Cheek1993SpatialLO,
  title={Spatial localization of agonist-induced Ca2+ entry in bovine adrenal chromaffin cells. Different patterns induced by histamine and angiotensin II, and relationship to catecholamine release.},
  author={T. Cheek and A. Morgan and A. J. O'Sullivan and R. Moreton and M. Berridge and R. Burgoyne},
  journal={Journal of cell science},
  year={1993},
  volume={105 ( Pt 4)},
  pages={
          913-21
        }
}
  • T. Cheek, A. Morgan, +3 authors R. Burgoyne
  • Published 1993
  • Biology, Medicine
  • Journal of cell science
  • The spatial organization of agonist-induced Ca2+ entry in single bovine adrenal chromaffin cells has been investigated using video-imaging techniques to visualize fura-2 quenching by the Ca2+ surrogate, Mn2+. The potent secretagogue histamine, in addition to releasing Ca2+ from intracellular stores, resulted in a large influx of external Mn2+ that occurred over the entire surface of the cell. The influx of Ca2+ that this mirrors was found to be an obligatory requirement for the triggering of… CONTINUE READING
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