Spatial heterogeneity and the persistence of infectious diseases.

  title={Spatial heterogeneity and the persistence of infectious diseases.},
  author={Thomas J. Hagenaars and Christl A. Donnelly and Neil M. Ferguson},
  journal={Journal of theoretical biology},
  volume={229 3},
The endemic persistence of infectious diseases can often not be understood without taking into account the relevant heterogeneities of host mixing. Here, we consider spatial heterogeneity, defined as 'patchiness' of the host population. After briefly reviewing how disease persistence is influenced by population size, reproduction number and infectious period, we explore its dependence on the level of spatial heterogeneity. Analysis and simulation of disease transmission in a symmetric meta… CONTINUE READING

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