Spatial distribution of "tissue-specific" antigens in the developing human heart and skeletal muscle. III. An immunohistochemical analysis of the distribution of the neural tissue antigen G1N2 in the embryonic heart; implications for the development of the atrioventricular conduction system.

@article{Wessels1992SpatialDO,
  title={Spatial distribution of "tissue-specific" antigens in the developing human heart and skeletal muscle. III. An immunohistochemical analysis of the distribution of the neural tissue antigen G1N2 in the embryonic heart; implications for the development of the atrioventricular conduction system.},
  author={Andy Wessels and Jacqueline L. M. Vermeulen and Fons J. Verbeek and Szabolcs Vir{\'a}gh and Fl{\'o}ra K{\'a}lm{\'a}n and Wout Lamers and Antoon F. M. Moorman},
  journal={The Anatomical record},
  year={1992},
  volume={232 1},
  pages={
          97-111
        }
}
A monoclonal antibody raised against an extract from the Ganglion Nodosum of the chick and designated G1N2 proves to bind specifically to a subpopulation of cardiomyocytes in the embryonic human heart. In the youngest stage examined (Carnegie stage 14, i.e., 4 1/2 weeks of development) these G1N2-expressing cells are localized in the myocardium that surrounds the foramen between the embryonic left and right ventricle. In the lesser curvature of the cardiac loop this "primary" ring occupies the… CONTINUE READING

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