Spatial control of coated-pit dynamics in living cells

@article{Gaidarov1999SpatialCO,
  title={Spatial control of coated-pit dynamics in living cells},
  author={Ibragim Gaidarov and Francesca Santini and Robin A. Warren and James H. Keen},
  journal={Nature Cell Biology},
  year={1999},
  volume={1},
  pages={1-7}
}
Here we visualize new aspects of the dynamics of endocytotic clathrin-coated pits and vesicles in mammalian cells by using a fusion protein consisting of green fluorescent protein and clathrin light chain a. Clathrin-coated pits invaginating from the plasma membrane show definite, but highly limited, mobility within the membrane that is relaxed upon treatment with latrunculin B, an inhibitor of actin assembly, indicating that an actin-based framework may be involved in the mobility of these… 

Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

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Dynamics and Cargo Selectivity of Endocytic Adaptor Proteins

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Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi network.

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Understanding Living Clathrin‐Coated Pits

The direct observation of CCP‐associated proteins including clathrin itself, dynamin and, most recently, AP‐2 has considerably challenged old models, confirming some points but raising very interesting new questions.
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