Spatial changes in calcium signaling during the establishment of neuronal polarity and synaptogenesis

@article{Verderio1994SpatialCI,
  title={Spatial changes in calcium signaling during the establishment of neuronal polarity and synaptogenesis},
  author={Claudia Verderio and Silvia Coco and G. Fumagalli and Michela Matteoli},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={126},
  pages={1527 - 1536}
}
Calcium imaging techniques were used to obtain a clear although indirect evidence about the distribution of functional glutamate receptors of NMDA and non-NMDA type in cultured hippocampal neurons during establishment of polarity and synaptogenesis. Glutamate receptors were expressed and were already functional as early as one day after plating. At this stage NMDA and non-NMDA receptors were distributed in all plasmalemmal areas. During the establishment of neuronal polarity, responses to… CONTINUE READING