Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes

@inproceedings{Riglar2013SpatialAW,
  title={Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes},
  author={David T. Riglar and Kelly L Rogers and Eric Hanssen and Lynne Turnbull and Hayley E. Bullen and Sarah C Charnaud and Jude M Przyborski and Paul R Gilson and Cynthia B Whitchurch and Brendan Crabb and Jake Baum and Alan F Cowman},
  booktitle={Nature communications},
  year={2013}
}
Export of proteins into the infected erythrocyte is critical for malaria parasite survival. The majority of effector proteins are thought to export via a proteinaceous translocon, resident in the parasitophorous vacuole membrane surrounding the parasite. Identification of the Plasmodium translocon of exported proteins and its biochemical association with exported proteins suggests it performs this role. Direct evidence for this, however, is lacking. Here using viable purified Plasmodium… CONTINUE READING