Spatial Working and Reference Memory in Rats Bred for Autonomic Sensitivity to Cholinergic Stimulation: Acquisition, Accuracy, Speed, and Effects of Cholinergic Drugs

@article{Bushnell1995SpatialWA,
  title={Spatial Working and Reference Memory in Rats Bred for Autonomic Sensitivity to Cholinergic Stimulation: Acquisition, Accuracy, Speed, and Effects of Cholinergic Drugs},
  author={Philip J. Bushnell and Edward D. Levin and David H. Overstreet},
  journal={Neurobiology of Learning and Memory},
  year={1995},
  volume={63},
  pages={116-132}
}
Rat lines were selected by breeding for sensitivity to signs of autonomic stimulation (hypotherma, loss of body weight, and reduced water intake) induced by the cholinesterase inhibitor diisopropyl fluorophosphate (DFP). These lines have since been maintained for 10 generations by continued selection for hypothermic responsiveness to the muscarinic agonist oxotremorine. The sensitive rats (Flinders Sensitive Line, FSL) differ from the resistant rats (Flinders Resistant Line, FRL) both… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…