Spatial Object Recognition Enables Endogenous LTD that Curtails LTP in the Mouse Hippocampus

@inproceedings{Goh2013SpatialOR,
  title={Spatial Object Recognition Enables Endogenous LTD that Curtails LTP in the Mouse Hippocampus},
  author={Jinzhong Jeremy Goh and Denise Manahan-Vaughan},
  booktitle={Cerebral cortex},
  year={2013}
}
Although synaptic plasticity is believed to comprise the cellular substrate for learning and memory, limited direct evidence exists that hippocampus-dependent learning actually triggers synaptic plasticity. It is likely, however, that long-term potentiation (LTP) works in concert with its counterpart, long-term depression (LTD) in the creation of spatial memory. It has been reported in rats that weak synaptic plasticity is facilitated into persistent plasticity if afferent stimulation is… CONTINUE READING
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