Spatial Neglect, Balint-Homes' and Gerstmann's Syndrome, and Other Spatial Disorders

  title={Spatial Neglect, Balint-Homes' and Gerstmann's Syndrome, and Other Spatial Disorders},
  author={Giuseppe Vallar},
  journal={CNS Spectrums},
  pages={527 - 536}
  • G. Vallar
  • Published 1 July 2007
  • Psychology, Biology
  • CNS Spectrums
ABSTRACT Brain-damaged patients with lesion or dysfunction involving the parietal cortex may show a variety of neuropsychological impairments involving spatial cognition. The more frequent and disabling deficit is the syndrome of unilateral spatial neglect that, in a nutshell, consists in a bias of spatial representation and attention ipsilateral to of extrapersonal, personal (ie, the body) space, or both, toward the side of the hemispheric lesion. The deficit is more frequent and severe after… 
A deficit of spatial remapping in constructional apraxia after right-hemisphere stroke.
Findings provide the first evidence for a deficit in remapping visual information across saccades underlying right-hemisphere constructional apraxia, which is consistent with the view that rightward eye movements result in lost remembered spatial information from previous fixations.
The right parietal lobe is critical for visual working memory
The Neural Substrates of Drawing: A Voxel-based Morphometry Analysis of Constructional, Hierarchical, and Spatial Representation Deficits
Strong evidence is provided that impairments in separate cognitive mechanisms linked to different brain lesions contribute to poor performance on complex figure copying tasks, and the argument that drawing depends on several cognitive processes operating via discrete neuronal networks is supported.
Gerstmann’s syndrome: where does it come from and what does that tell us?
It is proposed that the selective association of symptoms in pure Gerstmann’s syndrome could instead be explained by a white matter lesion at a very specific location that results in intraparietal disconnection, and suggests expanding the classical concept of disconnection from disruption along a single long-distance fiber tract to situations where a conjoint disruption of separate fiber tracts determines the clinical syndrome.
Combination of attentional and spatial working memory deficits in Bálint–Holmes syndrome
The impairment to deploy attention is considered here as a bilateral covert attention deficit and is hypothesized to result from processes maintaining a salience map over time (spatial working memory) and especially across saccades.
The history of the neurophysiology and neurology of the parietal lobe.
[Psychological assessment of visual hemispatial neglect: standardization and approbation of the modified digit cancellation test].
In healthy right-handed people, there was the bias of attention focus to the left, the decrease of asymmetry intensity of visual-spatial inattention during physiological aging and the presence of some clinical peculiarities of neglect in schizophrenia spectrum disorders and lateralized organic damages of the brain.


Extrapersonal Visual Unilateral Spatial Neglect and Its Neuroanatomy
The emerging pattern is that USN is a multifarious disorder, in which specific deficits are associated with damage localized in discrete brain regions and neural circuits, and concur with evidence from other domains to suggest a highly multicomponential neural and functional architecture of spatial cognition.
Spatial hemineglect in humans
  • G. Kerkhoff
  • Psychology, Biology
    Progress in Neurobiology
  • 2001
The anatomy of neglect without hemianopia: a key role for parietal–frontal disconnection?
Findings call attention to the role of parietal–frontal disconnection in the pathogenesis of neglect, which can make neglect generalised and enduring also in patients suffering only partial damage of the parietal-temporal cortex, and who would otherwise show more selective attentional impairments.
Brain-behavior correlations in hemispatial neglect using CT and SPECT
Damage in the parietal and anterior cingulate cortex and posterior white matter fiber bundles correlated with hemispatial neglect, suggesting that combining structural- and functional-imaging techniques with neurobehavioral analysis can elucidate brain-behavior relationships.
Neglect and prism adaptation: a new therapeutic tool for spatial cognition disorders.
These cognitive effects of prism adaptation suggest that prism adaptation does not act specifically on the ipsilesional bias characteristic of unilateral neglect but rehabilitates more generally the visuo-spatial functions attributed to the right cortical hemisphere.
Anosognosia for motor and sensory deficits after unilateral brain damage: a review.
It is made that anosognosia for sensory and motor neurological deficits should be considered as a multi-component syndrome, including a number of specific disorders that are due to the impairment of discrete monitoring systems, specific for the different supervised functions.