Spatial Distribution of Cerebral White Matter Lesions Predicts Progression to Mild Cognitive Impairment and Dementia

@inproceedings{Mortamais2013SpatialDO,
  title={Spatial Distribution of Cerebral White Matter Lesions Predicts Progression to Mild Cognitive Impairment and Dementia},
  author={Marion Mortamais and Christelle Reyn{\`e}s and Adam M. Brickman and Frank Anthony Provenzano and Jordan Muraskin and Florence Portet and C Berr and Jacques Touchon and A Bonaf{\'e} and E Le Bars and Jerome J. Maller and Chantal Meslin and Robert Sabatier and Karen Ritchie and Sylvaine Art{\'e}ro},
  booktitle={PloS one},
  year={2013}
}
CONTEXT White matter lesions (WML) increase the risk of dementia. The relevance of WML location is less clear. We sought to determine whether a particular WML profile, based on the density and location of lesions, could be associated with an increased risk of mild cognitive impairment (MCI) or dementia over the following 7 years. METHODS In 426 healthy subjects from a cohort of community-dwelling people aged 65 years and over (ESPRIT Project), standardized cognitive and neurological… CONTINUE READING
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