Spatial Control of Cytokinesis by Cdr2 Kinase and Mid1/Anillin Nuclear Export

@article{Almonacid2009SpatialCO,
  title={Spatial Control of Cytokinesis by Cdr2 Kinase and Mid1/Anillin Nuclear Export},
  author={Maria Almonacid and James B Moseley and Julie Janvore and Adeline Mayeux and Vincent Fraisier and P. Nurse and Anne Paoletti},
  journal={Current Biology},
  year={2009},
  volume={19},
  pages={961-966}
}
Maintaining genome integrity and cellular function requires proper positioning of the cell division plane. In most eukaryotes, cytokinesis relies on a contractile actomyosin ring positioned by intrinsic spatial signals that are poorly defined at the molecular level. Fission yeast cells assemble a medial contractile ring in response to positive spatial cues from the nucleus at the cell center and negative spatial cues from the cell tips. These signals control the localization of the anillin-like… CONTINUE READING
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