Spastic muscle cells are shorter and stiffer than normal cells.

@article{Fridn2003SpasticMC,
  title={Spastic muscle cells are shorter and stiffer than normal cells.},
  author={Jan Frid{\'e}n and Richard L. Lieber},
  journal={Muscle & nerve},
  year={2003},
  volume={27 2},
  pages={
          157-64
        }
}
The mechanical properties of isolated single muscle fiber segments were measured in muscle cells obtained from patients undergoing surgery for correction of flexion contractures secondary to static perinatal encephalopathy (cerebral palsy). "Normal" muscle cells from patients with intact neuromuscular function were also mechanically tested. Fiber segments taken from subjects with spasticity developed passive tension at significantly shorter sarcomere lengths (1.84 +/- 0.05 microm, n = 15) than… CONTINUE READING
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